Therefore, a fundamental difference appears to exist in the antigenic composition of the two organisms, which was also demonstrated by cross-absorption in passive cutaneous anaphylaxis test ( PCAs ).
2.
Rather, they find that : "'a ) "'cells expressing both CysLTR1 and GPR17 receptors exhibit a marked reduction in binding and responding to LTD4 and "'b ) "'mice lacking GPR17 are hyper-responsive to igE in a model for passive cutaneous anaphylaxis.
3.
However, more recent studies from different laboratories could not confirm these results; they found that GPR17-bearing cells did not respond to these CysLTs or nucleotides but did find that cells expressing both CysLTR1 and GPR17 receptors exhibited a marked reduction in binding LTC4 and that mice lacking GPR17 were hyper-responsive to igE-induced passive cutaneous anaphylaxis.
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